CINCINNATI (AP) — Brandon Phillips, Eugenio Suarez and Zack Cozart homered in a five-run second inning, and the Cincinnati Reds beat Jake Peavy for the first time in a 7-4 win over the San Francisco Giants on Wednesday.

Adam Duvall added a solo shot for the Reds, and Dan Straily (1-1) overcame solo homers by Brandon Belt and Conor Gillaspie for his first major league win since April 10, 2014, with Oakland. Cincinnati avoided getting swept in the three-game series.

Mac Williamson and Denard Span hit consecutive two-out doubles in the ninth off Ross Ohlendorf. Cincinnati’s bullpen has allowed runs in a big league record 22 consecutive games.

Peavy (1-3) allowed seven runs and eight hits in six innings with eight strikeouts and one walk, raising his ERA to 9.00 in six starts. He had been 7-0 with a 2.38 ERA in 12 starts against the Reds.

Straily gave up three runs and six hits in 6 1/3 innings, helping stop the Giants’ three-game winning streak.

Phillips led off the second inning with his second homer of the season and first in 22 games since April 8. Suarez and Cozart followed with two-run drives, giving the Reds as many runs in one inning as they had scored against Peavy in any of his previous 12 career starts.

The three-homer inning was the first of Peavy’s 15-year big career. He’d allowed just two in his previous five starts .

Joey Votto doubled leading off the third and scored on Suarez’s two-out single for a 6-1 lead. Duvall hit his fourth homer of the season in the sixth.

TRAINING ROOM

Giants: RHP Sergio Romo, on the disabled list since April 15 with a flexor strain in his pitching arm, played catch at 90 feet on flat ground.

Reds: SS Zack Cozart started on Wednesday after leaving Sunday’s game at Pittsburgh and missing the next two games with tendinitis in his surgically repaired right knee.

UP NEXT

Giants: RHP Matt Cain (0-3) is the scheduled starter for Thursday’s opener of a four-game home series against Colorado.

Reds: RHP Alfredo Simon (0-3) makes his sixth appearance and fifth start of the season in Thursday’s opener of a four-game series against Milwaukee. The Reds are 0-5 when Simon pitches.

Cincinnati Reds pitcher Dan Straily throws against the San Francisco Giants during the second inning of a baseball game, Wednesday, May 4, 2016, in Cincinnati. (AP Photo/Gary Landers)

http://aimmedianetwork.com/wp-content/uploads/sites/22/2016/05/web1_110147350-2205b87576fc46b5936249b8d1cf5e5b.jpgCincinnati Reds pitcher Dan Straily throws against the San Francisco Giants during the second inning of a baseball game, Wednesday, May 4, 2016, in Cincinnati. (AP Photo/Gary Landers)

San Francisco Giants starting pitcher Jake Peavy throws against the Cincinnati Reds during the first inning of a baseball game, Wednesday, May 4, 2016, in Cincinnati. (AP Photo/Gary Landers)

http://aimmedianetwork.com/wp-content/uploads/sites/22/2016/05/web1_110147350-11ae6e5f7a76406d9d22a3506938e878.jpgSan Francisco Giants starting pitcher Jake Peavy throws against the Cincinnati Reds during the first inning of a baseball game, Wednesday, May 4, 2016, in Cincinnati. (AP Photo/Gary Landers)

San Francisco Giants’ Brandon Belt, right, is congratulated by third base coach Roberto Kelly (39) as he rounds the bases after hitting a solo home run during the second inning of a baseball game against the Cincinnati Reds, Wednesday, May 4, 2016, in Cincinnati. (AP Photo/Gary Landers)

http://aimmedianetwork.com/wp-content/uploads/sites/22/2016/05/web1_110147350-ab54ad2b440e4c4c813af1998d38d541.jpgSan Francisco Giants’ Brandon Belt, right, is congratulated by third base coach Roberto Kelly (39) as he rounds the bases after hitting a solo home run during the second inning of a baseball game against the Cincinnati Reds, Wednesday, May 4, 2016, in Cincinnati. (AP Photo/Gary Landers)